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1.
RAIRO: Recherche Opérationnelle ; 56:3311-3339, 2022.
Article in English | ProQuest Central | ID: covidwho-2050585

ABSTRACT

In today’s systems and networks, disruption is inevitable. Designing a reliable system to overcome probable facility disruptions plays a crucial role in planning and management. This article proposes a reliable capacitated facility joint inventory-location problem where location-independent disruption may occur in facilities. The system tries to satisfy customer’s demands and considers penalty costs for unmet customer demand. The article aims to minimize total costs such as establishing inventory, uncovered demand’s penalty, and transportation costs. While many articles in this area only use exact methods to solve the problem, this article uses a metaheuristic algorithm, the red deer algorithm, and the exact methods. Various numerical examples have shown the outstanding performance of the red deer algorithm compared to exact methods. Sensitivity analyses show the impacts of various parameters on the objective function and the optimal facility layouts. Lastly, managerial insights will be proposed based on sensitivity analysis.

2.
Vaccine ; 39(3): 495-504, 2021 01 15.
Article in English | MEDLINE | ID: covidwho-968914

ABSTRACT

The addition of other respiratory illnesses such as flu could cripple the healthcare system during the coronavirus disease 2019 (COVID-19) pandemic. An annual seasonal influenza vaccine is the best way to help protect against flu. Fears of coronavirus have intensified the shortage of influenza shots in developing countries that hope to vaccinate many populations to reduce stress on their health services. We present an inventory-location mixed-integer linear programming model for equitable influenza vaccine distribution in developing countries during the pandemic. The proposed model utilizes an equitable objective function to distribute vaccines to critical healthcare providers and first responders, elderly, pregnant women, and those with underlying health conditions. We present a case study in a developing country to exhibit efficacy and demonstrate the optimization model's applicability.


Subject(s)
COVID-19/epidemiology , Developing Countries/statistics & numerical data , Equipment and Supplies , Influenza Vaccines/supply & distribution , Public Health/methods , Aged , Aged, 80 and over , Female , Health Personnel , Humans , Influenza Vaccines/administration & dosage , Influenza, Human/prevention & control , Pregnancy , Vaccination
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